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CAS 5104-49-4 Top Quality Flurbiprofen for Antiinflammatory

Basic Info

Model No.:  5104-49-4

Product Description

Model NO.: 5104-49-4 Customized: Non-Customized Suitable for: Elderly, Children, Adult Purity: >99% CAS: 5104-49-4 MW: 244.26 Discount: Multiple Items Ordered One Time Shipping: Express Courier(EMS, DHL, UPS, TNT, FedEx) Transport Package: Foil Bag Origin: China Powder: Yes Certification: GMP, HSE, ISO 9001, USP, BP State: Solid Name: Flurbiprofen Mf: C15h13fo2 Einecs: 225-827-6 Delivery: Within 24 Hours Trademark: Shuangbojie Specification: ISO9001 HS Code: 2916399090 CAS 5104-49-4 Top Quality Flurbiprofen for Antiinflammatory 

1.  Flurbiprofen Detail:

Name: Flurbiprofen
Synonyms: 1'-biphenyl)-4-aceticacid,2-fluoro-alpha-methyl-(;1'-biphenyl]-4-aceticacid,2-fluoro-alpha-methyl-[;
2-(2-Fluoro-4-biphenyl)propionicacid;2-(2-fluoro-4-biphenylyl)propionicacid;2-fluoro-alpha-methyl-4-biphenylaceticaci;2-Fluoro-a-methyl-(1,1'-biphenyl)-4-aceticacid
CAS: 5104-49-4
Molecular Weight: 244.26
Molecular Formula: C15H13FO2
EINECS: 225-827-6 
Appearance: White to Off-White Crystalline powder
Assay: 99%
Usage: Antipyretic analgesic anti-inflammatory drugs for rheumatoid arthritis, osteoarthritis, post-operative and various types of cancer pain relief
Flurbiprofen is a member of the phenyl alkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs) used to treat the inflammation and pain of arthritis. It is known as "Ansaid" marketed by "Froben" by Abbott.
Flurbiprofen is also used as an active ingredient in some kinds of throat lozenges (Strepsils Intensive).
A single enantiomer of flurbiprofen, tarenflurbil, is currently in clinical trials for the treatment of metastatic prostate cancer.
Packing: 1kg/foil bag

2. Flurbiprofen Description:

Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID). It may cause an increased risk of serious and sometimes fatal heart and blood vessel problems (eg, heart attack, stroke). The risk may be greater if you already have heart problems or if you take flurbiprofen for a long time. Do not use flurbiprofen right before or after bypass heart surgery.
Flurbiprofen may cause an increased risk of serious and sometimes fatal stomach ulcers and bleeding. Elderly patients may be at greater risk. This may occur without warning signs.

3. Flurbiprofen Applications:

Treating rheumatoid arthritis or osteoarthritis. It may also be used for other conditions as determined by your doctor.
Flurbiprofen is an NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

4. Flurbiprofen COA:
 
Test  Item
Analysis  Specification

Result

Description

A white or almost white crystalline power

Conforms

Appearance of solution

Clear and colourless

Conforms

Identification

A,B,C

Positives

Optical rotation

-0.1°~ +0.1°


Melting point

114~117°C

114.5~115.6°C

Heavy metals

NMT 10ppm

<10ppm



Related substances

 

Impurity A  NMT0.5%

0.06%

Individual impurity NMT0.2%

0.12%

Total impurity NMT1.0%

0.30%

Loss on drying NMT0.5%

0.28%

Sulphated ASH NMT0.1%

0.03%

Assay

99.0%~100.5%

99.9%

Conclusion 

Confirm 

5. Flurbiprofen Details:

Name:Flurbiprofen
CAS: 5104-49-4
MF: C15H13FO2
MW: 244.26
EINECS: 225-827-6
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals
Assay:99%
Usage:antiinflammatory, analgesic.An anti-inflammatory used as an analgesic.
Biological Activity: Potent inhibitor of cyclooxygenase (IC 50 values are 0.1 and 0.4 μ M for inhibition of human COX-1 and COX-2 respectively). Analgesic, anti-inflammatory and antipyretic in vivo . Inhibits tumor cell growth in vitro and in vivo . Also inhibits fibroblast proliferation in vitro .
Packing:25kg/paper barrel ,foil bag or as required
 
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