Legal White Prohormones Steroids Powder Misoprostol CAS 59122-46-2 for Terminate Pregnancy
Basic Info
Model No.: 59122-46-2
Product Description
Model NO.: 59122-46-2 Customized: Non-Customized Suitable for: Adult Purity: >99% Assay: 99% Molecular Weight: 382.54 Delivery: Within 24 Hours After Payment Confirmed Payment: Western Union, Moneygram, T/T Supply Capacity: 50000kg/Month Specification: ISO9001 HS Code: 29224999 Powder: Yes Certification: GMP, ISO 9001, USP State: Solid CAS: 59122-46-2 Molecular Formula: C22h38o5 Appearance: White Solid Shipping: Express Courier(EMS, DHL, UPS, TNT, FedEx) Packaging: Foil Bag or Tin Trademark: shuangbojie Origin: China Legal White Prohormones Steroids Powder Misoprostol CAS 59122-46-2 for Terminate Pregnancy
Misoprostol
CAS: 59122-46-2
MF: C22H38O5
MW: 382.54
Chemical Properties White Solid
Usage antiulcerative;prostaglandin E1 analog that inhibits gastric acid secretion
Usage A cytoprotective prostaglandin PGE1 analogue
Biological Activity Cytoprotective prostaglandin E 1 analog that displays agonist activity at EP receptors. K i values are 120, 250, 67 and 67 nM at cloned mouse EP 1 , EP 2 , EP 3 and EP 4 receptors respectively. Prevents NSAID-induced gastric ulceration.
Description:
Misoprostol (brand name Cytotec) is a prostaglandin. Misoprostol is a synthetic (man-made) prostaglandin that is used to reduce the risk of stomach ulcers in patients treated with nonsteroidal antiinflammatory drugs (NSAIDs, for example,aspirin, ibuprofen, etc.) that are used for pain and various inflammatory conditions, for example, arthritis. Misoprostol is used primarily in patients at high risk for stomach ulcers when treated with NSAIDs, for example, the elderly, patients with concomitant debilitating diseases, and patients with a history of ulcers. Prostaglandins are chemicals that are made within many organs of the body including the stomach. In the stomach, prostaglandins are believed to protect the inner lining of the stomach from the ulcer-producing effects of NSAIDs. Misoprostol is also used sometimes to treat ulcers and to induce labor. Misoprostol is used in combination with mifepristone to end an early pregnancy. Talk to your doctor about the possible risks of using this drug for your condition.
Application:
Misoprostol is a prostaglandin analog that is registered in over 60 countries for treatment and prevention of gastric ulcers caused by prolonged use of anti-inflammatory medications. Because misoprostol causes uterine contractions, it is useful for a variety of obstetric and gynecologic purposes.
Misoprostol is the generic form of the brand-name drug Cytotec, which is used to prevent ulcers in people who take certain arthritis or pain medicines. Misoprostol is a synthetic prostaglandin. It works by protecting the stomach lining and decreasing stomach acid secretion. Misoprostol is sometimes used off-label to end an early pregnancy. The drug is most effective when it's used in combination with or mifepristone. Misoprostol can be given orally, buccally (dissolved between the gums and cheek), or vaginally for this purpose.Misoprostol tablets will replace your natural prostaglandins so you can continue getting benefit from your NSAID painkiller. If you already have an ulcer, misoprostol will help it to heal.
Misoprostol Specification:
Misoprostol Usage:
Misoprostol is approved for use in the prevention of NSAID-induced gastric ulcers. It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration (e.g. with diclofenac in Arthrotec).
Misoprostol has other protective actions, but is only clinically effective at doses high enough to reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression.
However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol,but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses (typically four) are the main issues impairing compliance with therapy.
The most commonly reported adverse effect of taking a misoprostol orally for the prevention of stomach ulcers is diarrhea. In clinical trials, an average 13% of patients reported diarrhea, which was dose-related and usually developed early in the course of therapy (after 13 days) and was usually self-limiting (often resolving within 8 days), but sometimes (in 2% of patients) required discontinuation of misoprostol.
The next most commonly reported adverse effects of taking misoprostol orally for the prevention of gastric ulcers are: abdominal pain, nausea, flatulence, headache, dyspepsia, vomiting, and constipation, but none of these adverse effects occurred significantly more often than when taking placebos. In practice, fever is almost universal when multiple doses are given every 4 to 6 hours.
Misoprostol should not be taken by pregnant women to reduce the risk of NSAID-induced gastric ulcers because it increases uterine tone and contractions in pregnancy, which may cause partial or complete abortions, and because its use in pregnancy has been associated with birth defects.
Company Advantage :
Contact us if you need more details on Misoprostol. We are ready to answer your questions on packaging, logistics, certification or any other aspects about Steroids、Pharmaceutical Chemical. If these products fail to match your need, please contact us and we would like to provide relevant information.
Misoprostol
CAS: 59122-46-2
MF: C22H38O5
MW: 382.54
Chemical Properties White Solid
Usage antiulcerative;prostaglandin E1 analog that inhibits gastric acid secretion
Usage A cytoprotective prostaglandin PGE1 analogue
Biological Activity Cytoprotective prostaglandin E 1 analog that displays agonist activity at EP receptors. K i values are 120, 250, 67 and 67 nM at cloned mouse EP 1 , EP 2 , EP 3 and EP 4 receptors respectively. Prevents NSAID-induced gastric ulceration.
Description:
Misoprostol (brand name Cytotec) is a prostaglandin. Misoprostol is a synthetic (man-made) prostaglandin that is used to reduce the risk of stomach ulcers in patients treated with nonsteroidal antiinflammatory drugs (NSAIDs, for example,aspirin, ibuprofen, etc.) that are used for pain and various inflammatory conditions, for example, arthritis. Misoprostol is used primarily in patients at high risk for stomach ulcers when treated with NSAIDs, for example, the elderly, patients with concomitant debilitating diseases, and patients with a history of ulcers. Prostaglandins are chemicals that are made within many organs of the body including the stomach. In the stomach, prostaglandins are believed to protect the inner lining of the stomach from the ulcer-producing effects of NSAIDs. Misoprostol is also used sometimes to treat ulcers and to induce labor. Misoprostol is used in combination with mifepristone to end an early pregnancy. Talk to your doctor about the possible risks of using this drug for your condition.
Application:
Misoprostol is a prostaglandin analog that is registered in over 60 countries for treatment and prevention of gastric ulcers caused by prolonged use of anti-inflammatory medications. Because misoprostol causes uterine contractions, it is useful for a variety of obstetric and gynecologic purposes.
Misoprostol is the generic form of the brand-name drug Cytotec, which is used to prevent ulcers in people who take certain arthritis or pain medicines. Misoprostol is a synthetic prostaglandin. It works by protecting the stomach lining and decreasing stomach acid secretion. Misoprostol is sometimes used off-label to end an early pregnancy. The drug is most effective when it's used in combination with or mifepristone. Misoprostol can be given orally, buccally (dissolved between the gums and cheek), or vaginally for this purpose.Misoprostol tablets will replace your natural prostaglandins so you can continue getting benefit from your NSAID painkiller. If you already have an ulcer, misoprostol will help it to heal.
Misoprostol Specification:
| Product name | Misoprostol | |
| Appearance | White crystalline powder | |
| Chromatographic purity | Any individual impurity not more than 1.0% Total impurities not more than 2.0% | 0.27% 0.7% |
| Loss on drying | Not more than 0.5% | 0.1% |
| Residue on ignition | Not more than 0.2% | 0.1% |
| Residual solvents | Methanol≤3000ppm Methylene Chloride≤600ppm Chloroform≤60ppm Tetrahydrofuran≤720ppm | 350ppm Not detect out Not detect out Not detect out |
| Assay | Between 97.0% and 102.0% | 99.2% |
| Micronixation | 90% not more than 10 microns | 90% not more than 10 aicrons |
Misoprostol Usage:
Misoprostol is approved for use in the prevention of NSAID-induced gastric ulcers. It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration (e.g. with diclofenac in Arthrotec).
Misoprostol has other protective actions, but is only clinically effective at doses high enough to reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression.
However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol,but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses (typically four) are the main issues impairing compliance with therapy.
The most commonly reported adverse effect of taking a misoprostol orally for the prevention of stomach ulcers is diarrhea. In clinical trials, an average 13% of patients reported diarrhea, which was dose-related and usually developed early in the course of therapy (after 13 days) and was usually self-limiting (often resolving within 8 days), but sometimes (in 2% of patients) required discontinuation of misoprostol.
The next most commonly reported adverse effects of taking misoprostol orally for the prevention of gastric ulcers are: abdominal pain, nausea, flatulence, headache, dyspepsia, vomiting, and constipation, but none of these adverse effects occurred significantly more often than when taking placebos. In practice, fever is almost universal when multiple doses are given every 4 to 6 hours.
Misoprostol should not be taken by pregnant women to reduce the risk of NSAID-induced gastric ulcers because it increases uterine tone and contractions in pregnancy, which may cause partial or complete abortions, and because its use in pregnancy has been associated with birth defects.
Company Advantage :
| Company Competitive Advantage: | |
| 1. Rich experiences. | Our company is a professional production leading factory in China in pharmaceutical area of many years. Delivery areas of our products:US, UK, Canada, Australia, Brazil, Russia, Portugal, Latvia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium, Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Thailand, Israel and so on,and we have got very good feedback from our customers, we had established a long friendly relations Payment method: T/T, Western union, Moneygram,Bitcoin |
| 2. Discreet package | The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also take into consideration . |
| 3. Top quality. | High quality guarenteed, once any problem is found, the package would be reshipped for you |
| 4. Security Shipping | Shipping by express (FedEx,UPS,DHL,EMS), by air.The most professional forwarder would be recommanded for you. |
| 5,Shipping time | We have stock, so we can delivery quickly at the very day when receive the payment. |
| 6,Service | Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.Adhering to the principle of customer first conviction.we will provide the best and the most sincere services as possible as we can. |
| 7. High quality | High quality, best price, first-class service, high successful delivery rate .A discount would be given when you make a large order. |
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